Rabbit Secondary Antibodies
ABclonal Technology TAP2 Rabbit mAb
The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters ABC proteins transport various molecules across extra- and intra-cellular membranes ABC genes are divided into seven distinct subfamilies (ABC1 MDR TAP MRP ALD OABP GCN20 White) This protein is a member of the MDR TAP subfamily Members of the MDR TAP subfamily are involved in multidrug resistance This gene is located 7 kb telomeric to gene family member ABCB2 The protein encoded by this gene is involved in antigen presentation This protein forms a heterodimer with ABCB2 in order to transport peptides from the cytoplasm to the endoplasmic reticulum Mutations in this gene may be associated with ankylosing spondylitis insulin-dependent diabetes mellitus and celiac disease Alternative splicing of this gene produces products which differ in peptide selectivity and level of restoration of surface expression of MHC class I molecules
ABclonal Technology SMPD3/NSMase2 Rabbit mAb
Predicted to enable phosphatidic acid binding activity phosphatidylserine binding activity and sphingomyelin phosphodiesterase activity Predicted to be involved in positive regulation of exosomal secretion and sphingomyelin metabolic process Predicted to act upstream of or within several processes including animal organ development enzyme linked receptor protein signaling pathway and sphingolipid metabolic process Predicted to be located in Golgi apparatus and plasma membrane Predicted to be active in cytoplasm Biomarker of pulmonary emphysema
ABclonal Technology BTN2A1 Rabbit mAb
This gene encodes a member of the immunoglobulin superfamily The gene is located in a cluster of butyrophilin-like genes in the juxta-telomeric region of the major histocompatibility complex on chromosome 6 A pseudogene of this gene has been identified in this cluster The encoded protein is an integral plasma membrane protein involved in lipid fatty-acid and sterol metabolism Alterations in this gene may be associated with several disease states including metabolic syndrome Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene
Genscript Corporation MonoRab Rabbit Anti-scFv Cock
This product is specific for scFvs in various species (humanized mouse) various orders (VH-linker-VL VL-linker-VH) and various forms of scFv-based bispecific antibodies(DART BiTE TandAbs IgG(H)-scFv2 scFv-Fab-Fc etc) This product exhibits minimal cross-reactivity with human mouse goat and rabbit immunoglobulins
Cayman Chemical p120CATnInCTerm RabbIt 100uL
An MTH1 inhibitor (IC50 72 nM) selective for MTH1 over a panel of 456 kinases at 1 UM induces oxidative DNA damage and apoptosis in SGC-7901 and BGC-823 cancer cells at 30 UM induces ROS production and apoptosis in the same model inhibits proliferation in a panel of 14 cancer cell lines expressing wild-type or various mutant forms of K-Ras or p53 (IC50s 0.52-7.4 UM) inhibits tumor growth in an SW 480 mouse xenograft model at 25 mg/kg
Cayman Chemical IgG3humn RabbIt Monclona 100ug
Immunogen: Human IgG3 • Host: Rabbit • Species Reactivity: (+) Human • Cross Reactivity: (-) Human IgG1, IgG2, IgG4, IgM, IgA, IgD, IgE; (-) Cynomolgus monkey, goat, mouse, rat, or rhesus monkey IgG • Applications: ELISA, ICC, IHC
ABclonal Technology FKBP10 Rabbit mAb
The protein encoded by this gene belongs to the FKBP-type peptidyl-prolyl cis trans isomerase (PPIase) family This protein localizes to the endoplasmic reticulum and acts as a molecular chaperone Alternatively spliced variants encoding different isoforms have been reported but their biological validity has not been determined
Cayman Chemical PaxIlInaN-Term RabbIt 100uL
A partial agonist of muscarinic acetylcholine receptors (Kis 5 1 5 0.2 and 7.6 UM for M1-5 receptors respectively in radioligand binding assays) induces contraction of isolated human umbilical veins (EC50 1.23 UM) intrathecal administration inhibits GNTI-induced compulsive hindlimb neck-scratching behavior in mice enhances spontaneous working memory in the Y maze in wild-type mice and reverses learning and memory impairments induced by bulbectomy in mice in a passive avoidance test
ABclonal Technology TR1/THRB Rabbit mAb
The protein encoded by this gene is a nuclear hormone receptor for triiodothyronine It is one of the several receptors for thyroid hormone and has been shown to mediate the biological activities of thyroid hormone Knockout studies in mice suggest that the different receptors while having certain extent of redundancy may mediate different functions of thyroid hormone Mutations in this gene are known to be a cause of generalized thyroid hormone resistance (GTHR) a syndrome characterized by goiter and high levels of circulating thyroid hormone (T3-T4) with normal or slightly elevated thyroid stimulating hormone (TSH) Several alternatively spliced transcript variants encoding the same protein have been observed for this gene
ABclonal Technology MMP1 Rabbit mAb
This gene encodes a member of the peptidase M10 family of matrix metalloproteinases (MMPs) Proteins in this family are involved in the breakdown of extracellular matrix in normal physiological processes such as embryonic development reproduction and tissue remodeling as well as in disease processes such as arthritis and metastasis The encoded preproprotein is proteolytically processed to generate the mature protease This secreted protease breaks down the interstitial collagens including types I II and III The gene is part of a cluster of MMP genes on chromosome 11 Mutations in this gene are associated with chronic obstructive pulmonary disease (COPD) Alternative splicing results in multiple transcript variants at least one of which encodes an isoform that is proteolytically processed
Cayman Chemical IgEhumn RabbIt Monclonal 100ug
Immunogen: Human IgE • Host: Rabbit • Species Reactivity: (+) Human • Cross Reactivity: (+) Human IgE; (-) Human IgG, IgA, IgD, IgM • Application: ELISA
Genscript Corporation MonoRab Rabbit Anti-scFv Cock
This product is specific for scFvs in various species (humanized mouse) various orders (VH-linker-VL VL-linker-VH) and various forms of scFv-based bispecific antibodies(DART BiTE TandAbs IgG(H)-scFv2 scFv-Fab-Fc etc) This product exhibits minimal cross-reactivity with human mouse goat and rabbit immunoglobulins
ABclonal Technology ITPR3 Rabbit mAb
This gene encodes a receptor for inositol 1 4 5-trisphosphate a second messenger that mediates the release of intracellular calcium The receptor contains a calcium channel at the C-terminus and the ligand-binding site at the N-terminus Knockout studies in mice suggest that type 2 and type 3 inositol 1 4 5-trisphosphate receptors play a key role in exocrine secretion underlying energy metabolism and growth